Tirzepatidesynthesis Tirzepatide has emerged as a significant compound in the pharmaceutical landscape, particularly for its applications in managing type 2 diabetes and facilitating weight loss.tirzepatide This article delves into the intricate details of tirzepatide, examining its classification, chemical properties, and its role as a therapeutic agent, drawing extensively from information available on platforms like PubChem.tirzepatide. Overview · Prescribing Info · Drug Label Annotations · Summary ... PubChem). Synonyms. L-tyrosyl-2-methylalanyl-L-alpha-glutamylglycyl-L-threonyl ... Understanding tirzepatide PubChem provides a crucial window into the scientific underpinnings of this innovative drug.
At its core, tirzepatide is a synthetic peptide characterized by its glucose-lowering effects.tirzepatide Its mechanism of action is distinguished by its dual agonism, targeting both the glucagon-like peptide-1 (GLP-1) receptor and the glucose-dependent insulinotropic polypeptide (GIP) receptor. This dual action allows it to stimulate both first- and second-phase insulin secretion while concurrently reducing glucagon levels. This dual GIP/GLP-1 agonist, sometimes referred to as a "twincretin," represents a novel class of antidiabetic agents.
The chemical identity of tirzepatide is detailed in various databases. Its molecular formula is often cited as C225H348N48O68, with an approximate molecular mass of 4813 g/molAzelaprag is under investigation in clinical trial NCT06515418 (Efficacy and Safety of Oral Azelaprag Plus Once WeeklyTirzepatideCompared WithTirzepatide.... For instance, PubChem CID 156588324 provides extensive details on tirzepatide, including its structure and chemical namesSemaglutide. Another related entry, PubChem CID 172874756, specifically details the Tirzepatide (sodium salt), highlighting variations in its chemical composition. The complexity of its structure, often described with numerous defined stereocenters such as in D-[Ala]18-Tirzepatide (CID 176453327), underscores its sophisticated peptide natureTirzepatide - Peptide Advantages. Information regarding its tirzepatide chemical formula and tirzepatide molecular weight are readily accessible through these resources.Tirzepatide (sodium salt) | C225H349N48NaO68 | CID 172874756 - structure, chemical names, physical and chemical properties, classification, patents, ...
Tirzepatide is administered via subcutaneous injections, offering a convenient route for patients.Azelaprag is under investigation in clinical trial NCT06515418 (Efficacy and Safety of Oral Azelaprag Plus Once WeeklyTirzepatideCompared WithTirzepatide... Its therapeutic applications are primarily focused on treating type 2 diabetes mellitus (T2DM) and aiding in weight management. The efficacy of tirzepatide as an antidiabetic medication and for weight loss has been demonstrated in clinical trialsSemaglutide | C187H291N45O59 | CID 56843331 - PubChem. It is important to note that tirzepatide is an approved treatment for adults with Type 2 diabetes, and its development signifies a major advancement in the fieldTirzepatide Once Weekly for the Treatment of Obesity.
Beyond tirzepatide, related compounds and analogs are also of interest. For example, Retatrutide (LY3437943) is another peptide that shares some functional similarities.Azelaprag is under investigation in clinical trial NCT06515418 (Efficacy and Safety of Oral Azelaprag Plus Once WeeklyTirzepatideCompared WithTirzepatide... Information on Retatrutide (LY3437943), 99.4% purity peptide can also be found alongside tirzepatide data on platforms like PubChem. Understanding the tirzepatide sequence and potential tirzepatide synthesis pathways are areas of ongoing research interest, often detailed within patent literature such as Patent CA-3208208-A1, which is summarized in databases like PubChem.
The classification of tirzepatide as a peptide and an antidiabetic agent, specifically within the class of DG01493 GLP-1 receptor agonists, further solidifies its therapeutic positioning. While its primary uses are well-established, ongoing research explores its potential in conjunction with other agents, as seen in investigations like clinical trial NCT06515418 involving oral Azelaprag plus tirzepatide.
For those seeking detailed reference information, PubChem serves as a vital repository. Entries such as SID 384585338 for tirzepatide(JAN/USAN) provide status updates and links to related compounds, including the marketed drug product Mounjaro (TN)Retatrutide (LY3437943), 99.4% purity peptide; Molecular Weight. 4731.33 ; CAS No. 2381089-83-2 ; PubChem CID. 485663353 ; Source. Synthetic ; Form. Powder.. The compound's synonyms and identifiers, such as PubChem CID 384585338 and ChEBI 194186, facilitate precise identification.
While generally considered safe and effective when prescribed by a healthcare professional, understanding potential nuances is crucial. For instance, information regarding its presence in breastmilk, as detailed in the Tirzepatide - Drugs and Lactation Database (LactMed®), suggests it is usually undetectable with common subcutaneous dosesThis web page summarizes information inPubChemabout patent CA-3208208-A1. This includes chemicals mentioned, as reported byPubChemcontributors, ....
In summary, tirzepatide PubChem data confirms its status as a groundbreaking synthetic peptide with a dual GIP/GLP-1 receptor agonist mechanism. Its chemical composition, detailed regulatory approvals by the FDA, and demonstrated efficacy in managing type 2 diabetes and obesity underscore its significance in modern pharmacotherapy.tirzepatide | C225H347N47O69 The accessibility of this information on platforms like PubChem is instrumental for researchers, healthcare providers, and informed patients alikeSummary of Use during Lactation.Tirzepatideis usually undetectable in breastmilk with subcutaneous doses of up to 5 mg..
Join the newsletter to receive news, updates, new products and freebies in your inbox.